Vaccines are a much debated topic in our communities today with an underlying concern for the safety of our children and communities. It is likely that every person has heard “vaccines are safe and effective” and “the science is done”, however, science evolves overtime and what is safe and effective today, may change tomorrow. Vaccines, like all commercially available pharmaceutical products, carry the risk for injury, death and failure. They also hold the unique status of being essentially liability free when they cause harm. This presentation will clarify why vaccination is a medical risk-taking procedure subject to the human right of informed consent, vaccine reaction reporting, vaccine policies and mandates, science informing risk and vaccine injury compensation and resources.